Conor Cunningham offers a critique of the kind of "ultra-Darwinist" materialism, in particular its epistemological incoherence:
As Cunningham points out, if everything we believe in is an illusion, including not only our understanding of God or our sense of self, but anything that we believe to be true about our world. It creates a self-destructive paradox: Materialism is in this regard no more a "true" description of the world than religion is, it is simply one meme among others, and gives us no more reliable a guide to the way that the world "really" is. Materialism this throughgoing, Cunningham points out, "fatally undermines itself.
Perhaps it is for this reason that so many materialists are so eager to keep the full implications of metaphysical materialism under wraps.